What is the 4-Methylmorpholine N-oxide?

4-Methylmorpholine N-oxide is Clear colorless to yellow solution, while it's Molecular Formula is C5H11NO2. Clear colorless to yellow solution Non-metallic catalyst for the cyanosilylation of ketones. Co-oxidant for Sharpless asymmetric dihydroxylation in ionic liquids.

What is the CAS number for 4-Methylmorpholine N-oxide?

The CAS number of 4-Methylmorpholine N-oxide is 7529-22-8.

What is 4-Methylmorpholine N-oxide (7529-22-8) used for?

4-Methylmorpholine N-oxide, also known as N-Methylmorpholine N-oxide, is an organic compound that serves as a versatile co-oxidant and catalyst in various chemical reactions. It is a metabolite of Morpholine and is recognized for its ability to dissolve cellulose and scleroproteins, making it a valuable component in the production of textiles and fibers.InChI:InChI=1/C5H11NO2/c1-6(7)2-4-8-5-3-6/h2-5H2,1H3

What is the 4-Methylmorpholine N-oxide?

4-Methylmorpholine N-oxide is Clear colorless to yellow solution, while it's Molecular Formula is C5H11NO2. Clear colorless to yellow solution Non-metallic catalyst for the cyanosilylation of ketones. Co-oxidant for Sharpless asymmetric dihydroxylation in ionic liquids.

What is the CAS number for 4-Methylmorpholine N-oxide?

The CAS number of 4-Methylmorpholine N-oxide is 7529-22-8.

What is 4-Methylmorpholine N-oxide (7529-22-8) used for?

4-Methylmorpholine N-oxide, also known as N-Methylmorpholine N-oxide, is an organic compound that serves as a versatile co-oxidant and catalyst in various chemical reactions. It is a metabolite of Morpholine and is recognized for its ability to dissolve cellulose and scleroproteins, making it a valuable component in the production of textiles and fibers.InChI:InChI=1/C5H11NO2/c1-6(7)2-4-8-5-3-6/h2-5H2,1H3

7529-22-8

Product Name:4-Methylmorpholine N-oxide
Molecular Formula:C₅H₁₁NO₂
Molecular Weight:117.148

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Product Details

Detail

Cas No： 7529-22-8
Molecular Formula： C₅H₁₁NO₂
Appearance： Clear colorless to yellow solution
Purity： 99%

Product Name	4-Methylmorpholine N-oxide
Alias	N-Methyl morpholine-N-oxide ; NMO
English
Molecular formula	C5H11NO2
Molecular weight	117.15
CAS No	7529-22-8
EINECS	231-391-8
Specification	Solid： assay :97% min liquid： 50 wt% in H2O ，60 wt. % in H2O
Appearance traits	Solid： light yellow crystal liquid： colorless transparent liquid
Use	Use for Organic Synthesis, catalyzer of epoxy resin , solvent of cellulose solution , heat stabilizers
Package	Solid: 25KG net fibreboard drum Liquid:200kg net drum
Other product information	Hazard: None Molecular Structure:

Factory supply 4-Methylmorpholine N-oxide 7529-22-8 (N-Methylmorpholine oxide) with low price

Molecular Formula:C5H11NO2
Molecular Weight:117.148
Appearance/Colour:Clear colorless to yellow solution
Vapor Pressure:1.41hPa at 20℃
Melting Point:180-184 °C
Refractive Index:n20/D 1.43
Boiling Point:118-119 °C
PKA:4.93±0.20(Predicted)
Flash Point:118-119ºC
PSA：38.66000
Density:1,14 g/cm³
LogP:-0.08020

4-Methylmorpholine N-oxide(Cas 7529-22-8) Usage

Flammability and Explosibility	Flammable
Purification Methods	When the oxide is dried for 2-3hours at high vacuum, it dehydrates. Add MeOH to the oxide and distil off the solvent under vacuum until the temperature is ca 95o. Then add Me2CO at reflux and cool to 20o. The crystals are filtered off, washed with Me2CO and dried. The degree of hydration may vary and may be important for the desired reactions. [van Rheenan et al. Tetrahedron Lett 1973 1076, Schneider & Hanze US Pat 2 769 823; see also Sharpless et al. Tetrahedron Lett 2503 1976.]
General Description	4-Methylmorpholine?N-oxide is an organic compound used as a co-oxidant along with OsO4 and ruthenates in organic synthesis. In recent studies, it has been used as a catalyst in silylcyanation of aldehydes and ketones. Lyocell, a regenerated cellulose fiber, can be prepared using 4-methylmorpholine?N-oxide in an eco-friendly manner.

InChI:InChI=1/C5H11NO2/c1-6(7)2-4-8-5-3-6/h2-5H2,1H3

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7529-22-8 Relevant articles

A concise synthesis of N-(trideuteromethyl)morpholine-N-oxide monohydrate

Rosenau, Thomas,Potthast, Antje,Kosma, Paul

, p. 1972 - 1974 (1999)

An efficient synthesis of N-(trideuterom...

PRODUCTION OF AN AMINE OXIDE BY OXIDATION OF A TERTIARY AMINE

-

Paragraph 0079, (2019/10/23)

A method for producing an amine oxide by...

Preparation method for N-methylmorpholine-N-oxide (NMMO)

-

Paragraph 0032-0053, (2019/10/08)

The invention provides a preparation met...

Optimized preparation method of N-methylmorpholine-N-oxide

-

Paragraph 0038-0059, (2019/12/02)

The invention belongs to the technical f...

Comparison of riboflavin-derived flavinium salts applied to catalytic H2O2 oxidations

Sakai, Takuya,Kumoi, Takuma,Ishikawa, Tatsuro,Nitta, Takahiro,Iida, Hiroki

supporting information, p. 3999 - 4007 (2018/06/08)

A series of flavinium salts, 5-ethylisoa...

7529-22-8 Process route

: 109-02-4
4-methyl-morpholine

: 7529-22-8
4-methylmorpholine N-oxide

Conditions

Conditions	Yield
With 4-hydroperoxy-5-ethyl-3-methyllumiflavine; In tert-butyl alcohol; at 30 ℃; Rate constant;	100%
With carbon dioxide; phosphoric acid; dihydrogen peroxide; for 0.133333h; under 7500.75 Torr; Reagent/catalyst; Pressure; Time; Autoclave;	100%
With dihydrogen peroxide; benzonitrile; Mg-Al-O-t-Bu HT (Catalyst B); In methanol; water; at 65 ℃; for 0.5h; Product distribution / selectivity;	98%
With oxidized flavin; oxygen; hydrazine hydrate; In 2,2,2-trifluoroethanol; at 60 ℃; for 2h; under 760.051 Torr;	97%
With dihydrogen peroxide; benzonitrile; Mg-Al-O-t-Bu HT (Catalyst C); In methanol; water; at 65 ℃; for 0.5h; Product distribution / selectivity;	97%
With dihydrogen peroxide; benzonitrile; Mg-Al-O-t-Bu HT (Catalyst D); In methanol; water; at 65 ℃; for 0.5h; Product distribution / selectivity;	97%
With dihydrogen peroxide; benzonitrile; Mg-Al-O-t-Bu HT (Catalyst E); In methanol; water; at 65 ℃; for 0.5h; Product distribution / selectivity;	97%
With dihydrogen peroxide; layered double hydroxide WO₄^(2-); at 20 ℃; for 1h;	96%
With dihydrogen peroxide; benzonitrile; Mg-Al-O-t-Bu HT (Catalyst A); In methanol; water; at 65 ℃; for 0.5h; Product distribution / selectivity;	96%
With 2,2,2-Trifluoroacetophenone; dihydrogen peroxide; acetonitrile; In tert-butyl alcohol; at 20 ℃; for 18h; chemoselective reaction; Green chemistry;	95%
With dihydrogen peroxide; benzonitrile; Mg-Al-O-t-Bu HT (Catalyst B); In water; at 65 ℃; for 0.5h; Product distribution / selectivity;	92%
With 2-hydroxyperoxyhexafluoro-2-propanol; In dichloromethane; at 0 ℃; for 0.166667h;	90%
With oxaziridinium tetrafluoroborate derived from N-methyl-1,2,3,4-tetrahydroisoquinoline; In dichloromethane; at -18 ℃;	90%
With dihydrogen peroxide; sodium hydrogencarbonate; trichloroacetonitrile; In tetrahydrofuran; water; at 0 - 25 ℃; for 4h;	89%
With dihydrogen peroxide; In water; at 20 ℃; for 3h;	83%
With 1,3-dimethyl-5-ethyl-5,10-dihydroalloxazine; dihydrogen peroxide; In methanol; water; for 2h; Ambient temperature;	75%
With dihydrogen peroxide; benzonitrile; potassium tert-butylate; In methanol; water; at 65 ℃; for 1.1h; Product distribution / selectivity;	75%
With iron(III) oxide; oxygen; isovaleraldehyde; In 1,2-dichloro-ethane; at 40 ℃; for 3h;	70%
With oxygen; ruthenium trichloride; In 1,2-dichloro-ethane; at 20 ℃; for 12h; under 760 Torr;	70%
With dihydrogen peroxide; In water; acetonitrile; at 80 ℃; for 4h; Green chemistry;	70%
With dihydrogen peroxide; at 70 - 75 ℃; for 4h;	67%
With oxygen; In water; at 115 ℃; for 72h; under 53254.2 Torr;	62%
With dihydrogen peroxide; In d⁽⁴⁾-methanol; water; rate enhancement in the presence of 1,3-dimethyl-5-ethyl-5,10-dihydroalloxazine;
With 3-bromo-4,5-dihydro-5-hydroperoxy-4,4-dimethyl-3,5-diphenyl-3H-pyrazole; In chloroform-d1; at 34 ℃; further reagents: MCPB;	95 % Spectr.
With dihydrogen peroxide; In methanol;
With 3,3-dimethyldioxirane; In dichloromethane; acetone; at 0 ℃;
With substituted 3-hydroperoxy-1,2-benzisothiazole 1,1-dioxide; In chloroform-d1; at 20 ℃; for 3h;	95 % Spectr.
With dihydrogen peroxide; In water; at 20 ℃;
With 3-chloro-benzenecarboperoxoic acid; In chloroform-d1;
With 3-chloro-benzenecarboperoxoic acid; In chloroform-d1;
With pyridine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 2h; chemoselective reaction;
With dihydrogen peroxide; In water; at 0 - 30 ℃;
With dihydrogen peroxide; In ethanol; at 65 - 70 ℃; for 6h;
With 5-ethyl-1,3,7,8-tetramethylalloxazinium triflate; dihydrogen peroxide; In d⁽⁴⁾-methanol; water; at 25 ℃; Reagent/catalyst;
With zinc(II) oxide; dihydrogen peroxide; In water; at 40 ℃; Temperature;
4-methyl-morpholine; With titanium(IV) oxide; for 0.333333h; With dihydrogen peroxide; at 40 ℃; Temperature;

: 4-[6-hydroxy-2,7,8-trimethyl-2-(4,8,12-trimethyl-tridecyl)-chroman-5-ylmethyl]-4-methyl-morpholin-4-ium; iodide

: 7529-22-8
4-methylmorpholine N-oxide

Conditions

Conditions	Yield
With sodium percarbonate; In hexane; dichloromethane; acetonitrile; at 50 ℃; for 1h;

7529-22-8 Upstream products

109-02-4
4-methyl-morpholine
76847-41-1
3-bromo-4,5-dihydro-5-hydroperoxy-4,4-dimethyl-3,5-diphenyl-3H-pyrazole
72229-10-8
cis-3-bromo-4,5-dihydro-5-hydroperoxy-4,4-dimethyl-3,5-diphenyl-3H-pyrazole
107743-45-3
C₁₇H₁₆⁽²⁾HBrN₂O₂