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1878-66-6

  • Product Name:4-Chlorophenylacetic acid
  • Molecular Formula:C8H7ClO2
  • Molecular Weight:170.595
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Product Details

Detail

  • Cas No： 1878-66-6
  • Molecular Formula： C8H7ClO2
  • Appearance： white to cream colored powder
  • Purity： 99%

Factory supply 4-Chlorophenylacetic acid 1878-66-6 (PCPA)  with low price

  • Molecular Formula:C8H7ClO2
  • Molecular Weight:170.595
  • Appearance/Colour:white to cream colored powder 
  • Vapor Pressure:0.000751mmHg at 25°C 
  • Melting Point:102-105 °C(lit.) 
  • Refractive Index:1.5660 (estimate) 
  • Boiling Point:294.1 °C at 760 mmHg 
  • PKA:4.19(at 25℃) 
  • Flash Point:131.7 °C 
  • PSA：37.30000 
  • Density:1.324 g/cm3 
  • LogP:1.96710 

4-Chlorophenylacetic acid(Cas 1878-66-6) Usage

Purification Methods

Purify it as for 3-chlorophenylacetic acid. [Beilstein 9 III 2263, 9 IV 1674.]

Definition

ChEBI: A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-chlorophenyl group.

General Description

4-Chlorophenylacetic acid possess anticancer properties. It is a novel therapeutic agent which can be useful in prevention or treatment of estrogen-sensitive breast cancer. It acts as carbon and energy supplement and is degraded by Pseudomonas sp. strain CBS3.

InChI:InChI=1/C8H7ClO2/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5H2,(H,10,11)/p-1

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1878-66-6 Relevant articles

Asymmetric Catalytic Alkylation of 4-Chlorophenylacetic Acid

Mi, A. Q.,Wang, Z. Y.,Jiang, Y. Z.

, p. 1957 - 1960 (1993)

Using N-(monoalkyl)-α,β-diphenyl-β-hydro...

α-thiocyanation of carbonyl and β-dicarbonyl compounds using (dichloroiodo)benzene-lead(II) thiocyanate

Prakash,Kaur,Batra,Rani,Singh,Moriarty

, p. 2019 - 2023 (2001)

The combination reagent (dichloroiodo)be...

Method for preparing carboxylic acid by one-pot method

-

Paragraph 0051-0055, (2021/01/29)

The invention discloses a method for pre...

Visible-Light-Enabled Carboxylation of Benzyl Alcohol Derivatives with CO2 Using a Palladium/Iridium Dual Catalyst

Iwasawa, Nobuharu,Jin, Yushu,Toriumi, Naoyuki

, (2021/12/14)

A highly efficient carboxylation of benz...

Alkali-modified heterogeneous Pd-catalyzed synthesis of acids, amides and esters from aryl halides using formic acid as the CO precursor

Fapojuwo, Dele Peter,Maqunga, Nomathamsanqa Prudence,Meijboom, Reinout,Mogudi, Batsile M.,Molokoane, Pule Petrus,Onisuru, Oluwatayo Racheal,Oseghale, Charles O.

, p. 26937 - 26948 (2021/08/17)

To establish an environmentally friendly...

Desulfonylative Electrocarboxylation with Carbon Dioxide

Zhong, Jun-Song,Yang, Zi-Xin,Ding, Cheng-Lin,Huang, Ya-Feng,Zhao, Yi,Yan, Hong,Ye, Ke-Yin

supporting information, p. 16162 - 16170 (2021/09/02)

Electrocarboxylation of organic halides ...

1878-66-6 Process route

2-(4-Chloro-phenyl)-N-methyl-N-(4-nitro-phenyl)-acetamide

2-(4-Chloro-phenyl)-N-methyl-N-(4-nitro-phenyl)-acetamide

4-chlorophenylacetic Acid
1878-66-6

4-chlorophenylacetic Acid

N-methyl(p-nitroaniline)
100-15-2

N-methyl(p-nitroaniline)

Conditions
Conditions Yield
With barium dihydroxide; cetyltrimethylammonim bromide; In water; at 30 ℃; Rate constant; Mechanism; dependence of rate constant on concentration of cetyltrimethylammonium bromide;
 
5-p-chlorophenyl-2-phenyl-4-tosyl-2-oxazoline
80225-01-0

5-p-chlorophenyl-2-phenyl-4-tosyl-2-oxazoline

4-chlorophenylacetic Acid
1878-66-6

4-chlorophenylacetic Acid

5-(4-chlorophenyl)-2-phenyl-1,3-oxazole
80224-89-1

5-(4-chlorophenyl)-2-phenyl-1,3-oxazole

p-toluene sulfinic acid
536-57-2

p-toluene sulfinic acid

benzamide
55-21-0,27208-38-4

benzamide

Conditions
Conditions Yield
With potassium carbonate; In methanol; for 1.5h; Yields of byproduct given; Heating;
14%

1878-66-6 Upstream products

  • 103-82-2
    103-82-2

    phenylacetic acid

  • 104-03-0
    104-03-0

    4-nitrobenzeneacetic acid

  • 1197-55-3
    1197-55-3

    4-aminophenylacetic acid

  • 15601-44-2
    15601-44-2

    (Z/E)-4-(4-chlorobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one

1878-66-6 Downstream products

  • 52449-43-1
    52449-43-1

    (4-chloro-phenyl)-acetic acid methyl ester

  • 14062-24-9
    14062-24-9

    4-chloro-benzeneacetic acid, ethyl ester

  • 5445-25-0
    5445-25-0

    ethyl 2-bromo-2-(4-chlorophenyl)acetate

  • 65622-34-6
    65622-34-6

    1,3-di(4-chlorophenyl)-2-propanone

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